Groundbreaking liver preservation device enables donor liver to safely journey over 2,000 miles from coast to coast

WALTHAM, MASSACHUSETTS – May 13, 2025 – Paragonix Technologies, Inc., a leader in organ preservation technology, announces an exciting achievement for its Paragonix LIVERguard^® System as the device safely preserved a donor liver during a recovery which covered the cross-country distance from the West Coast to North Carolina. This incredible journey resulted in successful transplant at Duke University Hospital, one of the largest organ transplant centers in the world. The case marks one of the longest liver procurements on record utilizing advanced hypothermic preservation and highlights the potential of this technology to procure more donor livers at greater distances, potentially enabling more life-saving transplants.

Duke University Hospital received a donor match on the West Coast for a patient on its waitlist. Historically due to the organs distance from the hospital, the team would have to seriously consider the impact of out of body time (cold ischemic time) of the organ for the recipient. As an early adopter of advanced hypothermic liver preservation technology, the transplant team felt confident that the technology would successfully preserve the organ in an optimal condition. This long-distance transplant case demonstrates the impact of advanced preservation technology on increasing access to donor organs, with this donor liver traveling over 2,000 nautical miles.

“Traditionally, geographical distance has played a crucial role in assessing donor organ suitability. The advent of innovative technologies such as advanced liver preservation now enables transplant centers to broaden their access to donor organs, facilitating better matches between recipients and available organs,” stated Dr. Andrew Barbas, Associate Professor of Surgery at Duke University Hospital.

More than 106,000 patients are currently on the national transplant waitlist in the U.S. Expanding donor pools and optimizing available resources is critical. Controlled hypothermic preservation has shown significant benefits for liver transplants. The LIVERguard system’s compact and easy-to-transport design combines stable cooling technology driven by real-time data monitoring, ensuring donor livers arrive in optimal condition and improving the process from donation to recipient.

“We are committed to honoring both the donor and recipient throughout the organ transplantation process," said Dr. Lisa Anderson, President of Paragonix Technologies. "By leveraging advanced technologies like LIVERguard, surgeons can now offer organs to patients that were previously inaccessible due to distance or prolonged ischemic time. This capability ensures the donor's gift is respected, allowing for optimal matches with recipients who are most in need.”

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